Okay, actually it's the New England offense vs. the Denver defense, and the Denver offense vs. the New England defense. Whatever.
Payton Manning is a dead quarterback who doesn't know he died of old age two years ago. Only a few people, me being one of them, are able to admit that the man is at least two years past his prime. Still, a dead Payton Manning is better than at least thirteen other NFL starting quarterbacks who are still alive, so... Not to mention that if you can get to Tom Brady with your front four you can beat him. If you have to blitz him, Tom Brady will kill you because the blitz will have left the secondary weakened, but Denver can get to him with their front four.
Denver by a score of 24-17.
I'll go with the Panthers, 38-31.